What dose-fractionation would you utilize for an unresectable localized cutaneous melanoma that has progressed on immunotherapy?

If the concern is to minimize the chance of radiation-induced brachial plexopathy, then it is advisable to keep the equivalent total dose below the tolerance of the brachial plexus. The preceding immunotherapy is not known to change the risk of radiation-induced brachial plexopathy. Contrary to popu...