What dosing schedule of cladribine do you use for newly diagnosed hairy cell leukemia in need of treatment?

Great question. For patients who meet criteria for treatment and have classic hairy cell leukemia, both the 7-day continuous infusion of cladribine and the 5-day daily dosing seem to have equal efficacy and toxicity. I think either is fine and patient preference can be considered. The 5-day scheme s...