What duration of ADT do you recommend for a patient with locally treated prostate cancer who undergoes metastasis-directed radiation therapy to a single oligometastatic bone lesion?

While I agree with @Dr. First Last that very small studies like STOMP and ORIOLE suggest that a small subset of men can delay the need for ADT by 1-3 years, this is not level 1 evidence. Most men with oligometastatic HSPC will still progress with metastasis directed therapy alone over a short time h...

Treating oligometastatic prostate cancer has become a point of great controversy in the field as this definition has relied on relatively soft definitions. Even in the case of a single bone metastasis detected by conventional CT or bone scan, PET imaging may identify more disease. Moreover, the imag...

I believe this is referring to a single metastasis identified at time of initial staging. For these patients, my default is to recommend long-term ADT. That is particularly true for patients whose metastasis was detected only with next-gen imaging, since these would have qualified for the RT+ADT tri...

18 months.

I tend to use 4- 6 months, though have used a year occasionally for larger lesions, strictly as a radiosensitizer, since we still don't achieve local control with SBRT in 100%, and is likely ADT's primary benefit here.

Current data suggests quicker and fuller recovery of testosterone levels with sh...