What endocrine therapy would you recommend for a perimenopausal female with a low risk Oncotype, HR+, HER2-negative, SLNB negative breast cancer who is clinically postmenopausal but with FSH, LH and estradiol that are not in the postmenopausal range?

Topics: Breast Cancer • Medical Oncology • HR+ • Breast Cancer, Non-metastatic

Answer from: Medical Oncologist at Academic Institution

In this situation, with a low risk, node-negative disease with ambivalent menopausal status, Tamoxifen, unless contraindicated, would be my choice. A SERM is equally effective for premenopausal and postmenopausal women. In the course of adjuvant endocrine therapy, changing to an aromatase inhibitor ...

Comments

Medical Oncologist at Riverside Methodist Hospitals/OhioHealth
Thank you! Would you monitor FSH, LH, and estradio...

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