What factors influence the decision between anti-VEGF injections and surgical displacement with tPA for treating submacular hemorrhage in AMD patients?

The size, thickness, and location of the heme are factors to consider between anti-VEGF monotherapy and a displacement procedure. If there is sufficient thickness to the heme and it is subfoveal, then I perform an in-office displacement. I usually inject anti-VEGF + intravitreal gas on day 0, and th...

In my experience, the speed at which I can get to the OR and the willingness of the patient to do surgery are the only factors that have affected the success of the surgery. If I can give an anti-VEGF on presentation and get to the OR within the week to inject subretinal tPA, then I have a chance to...