What first-line therapies do you recommend for patients with folliculotropic mycosis fungoides?

Agree with Dr. @Dr. First Last as above. For first-line topical therapies for patients with limited skin disease, you can consider topical steroids or topical nitrogen mustard, although these agents may not penetrate the skin to a sufficient depth to treat the disease at the hair follicle. Other opt...

Treatment of any patient with mycosis fungoides is highly specific and depends on many factors, such as the extent of the disease, overall patient health condition, and treatment goals. I recommend the following reference from the Cutaneous Lymphoma Foundation website (Folliculotropic mycosis fungoi...

I agree it depends on body surface involvement, thickness of plaques, if there is rapid progression or relative stability of plaques over time. If lesions look like they are forming tumors that is usually bad.

Also, if the patient looks colonized/impetigenized then it usually is a worse trajectory a...