Mednet Logo
CommunityRadiation Oncology

What is current practice for sparing a tissue strip in extremity radiation?

In a refractory DLBCL of entire circumference of leg below knee, how do you spare a tissue strip for lymph node drainage?
4 Answers
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · The Ohio State University - James Cancer Hospital and Solove Research Institute
Answered on · Updated on

So far as I am aware, RTOG 0630 is the only source for a "skin strip" constraint, and as @Dr. First Last mentions, the protocol does not fully specify how this was defined. ("No more than 50% of a longitudinal stripe of skin and subcutaneous tissue of an extremity should receive 2000 cGy. This strip...

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of North Carolina at Chapel Hill
Answered on

Since @Dr. First Last mentioned me in his post, I thought I would provide a bit of additional information. As he mentioned, Herman Suit, when he was at MD Anderson and pioneering much of the practice of radiation therapy in soft tissue sarcoma, treated a series of patients to high doses, often 70 Gy...

Join for free or sign in to see the full answer

Mednet Member
Mednet MemberInvited Expert
Radiation Oncology
Answered on

I don't know of any solid data which establishes a dose or volume relationship for toxicity related to circumferential radiation, but in RTOG 0630 [protocol link], which is a pre-op radiation for sarcoma protocol, the specified dose constraint for sparing a strip of skin was no more than 50% to rece...

Join for free or sign in to see the full answer

Mednet Member
Mednet Member
Radiation Oncology · LJA
Answered on

The use of skin/subcut strip sparing was pioneered by Dr. Herman Suit, initially at MDAH and then at MGH. In the 80s, Dr. @Dr. First Last joined Dr. Suit in a comprehensive Red Journal article on this and other techniques for sarcoma xrt.

Join for free or sign in to see the full answer