What is optimal therapy for a 5 year delayed recurrence of uterine cancer, rendered NED by solitary pulmonary metastasis resection?

I favor “pseudoadjuvant” therapy with carboplatin + paclitaxel chemotherapy for 6 cycles. I make this recommendation in the absence of strong data to suggest an improvement in outcome with chemotherapy over observation vs. hormonal therapy.

The optimal therapy for this patient with recurrent endomet...

Over the years, I have had several patients like this and after pulmonary resection, have just followed them without further therapy and to date no recurrence.

Not much data is available. Consideration of adjuvant therapy, in this case, depends on a number of factors. In a very elderly and frail patient, I would agree with Dr. @Dr. First Last and manage expectantly without any active treatment. In others, I would check ER/PR status and if positive, would t...