What is optimal timing or sequencing of therapy for patients with synchronous locally advanced triple negative breast cancer and ovarian cancer with peritoneal carcinomatosis?

Because delays in surgical healing can affect initiation of chemotherapy in ovarian cancer, I would consider neoadjuvant therapy for both the ovarian and breast cancer. Alternatively, one could do debunking surgery and then chemotherapy. I would recommend carboplatin q 3 weeks with taxol weekly x 6 ...

I agree with the chemotherapy, but I would never delay therapy for a locally advanced triple negative cancer. I would do neoadjuvant therapy and surgery later.

Genetic testing is critical here and the patient has a high chance of HRD-related mutation and consideration of a PARP inhibitor following t...