What is the flank radiation dose for recurrent Wilms?
Is radiation always indicated?
AREN 0532 specified 10.8Gy flank with 10.8Gy boost to gross residual in all recurrent Wilms patients. However, NWTS-5 recommended 21.6Gy flank with 9 Gy boost to gross residual for recurrent Wilm's.
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Northwestern University Feinberg School of Medicine
Answered on
For children with recurrent Wilms who had NO treatment with either chemo or RT, we recommend the lower doses mentioned in AREN0532 (NCT00352534).
All treatment- recurrent Wilms should receive higher doses as stated in NWTS5 (NCT00002611).
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