Topics:
Radiation Oncology • Pediatric Oncology
What is the flank radiation dose for recurrent Wilms?
Is radiation always indicated?
AREN 0532 specified 10.8Gy flank with 10.8Gy boost to gross residual in all recurrent Wilms patients. However, NWTS-5 recommended 21.6Gy flank with 9 Gy boost to gross residual for recurrent Wilm's.
Answer from: Radiation Oncologist at Academic Institution
For children with recurrent Wilms who had NO treatment with either chemo or RT, we recommend the lower doses mentioned in AREN0532 (NCT00352534).
All treatment- recurrent Wilms should receive higher doses as stated in NWTS5 (NCT00002611).
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