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What is the recommended management for a large unresectable intracranial hemangiopericytoma?

Is there a role for neoadjuvant radiotherapy prior to attempted embolization or resection? Do you routinely electively cover the location of prior surgical/biopsy tracts?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Mayo Clinic
Answered on

Although beyond the scope of this discussion, it is important to recognize the evolution of the pathological classification of hemangiopericytoma. Solitary fibrous tumor and hemangiopericytoma are now considered histopathological phenotypes of a single pathologic entity. However, past studies typically reported on these tumors as separate entities and one needs to be aware of this. Partly for this reason neuropathologists continue to divide these tumors into solitary fibrous tumor and hemangiopericytoma and will likely do so until further studies are available.

Hemangiopericytoma are rare tumors accounting for <1% of all primary CNS tumors and because of this our understanding of these tumors is limited. Most studies find better local contr...

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