What is the role of GammaTile in the management of primary brain tumors and brain metastases?

GammaTiles are an intracranial brachytherapy product marketed by GT Medical Technologies consisting of a Cs-131 source imbedded within a collagen matrix. Proponents of the technology argue that advantages of GammaTiles over external beam radiotherapy techniques include the ability to “start” the rad...

While surgically targeted radiotherapy (STaRT) implants may have a role in the delivery of adjuvant radiation following surgical resection, no specific delivery modality should be considered "routine". Post-operative SRS, along with pre-operative SRS, STaRT, and low-energy X-ray intraoperative radio...

In the setting of de-novo brain metastases, assuming the patient will go on to full-dose chemotherapy, possibly with immunotherapy (i.e. carbo/pem/pem if lung cancer). Given that the half-life of Cs131 is 9.2 days, how long would one wait after implant before administering full-dose chemotherapy?

T...