What is your approach to brain reirradiation in the setting of recurrent/progressive gliomas?
If a WHO II glioma was treated with RT and recurs and is now a WHO III glioma would you retreat with radiation? What would be your target volumes/margins? What would be your doses? Would this be something you would treat with an SRS approach?
2 Answers
Mednet Member
Radiation Oncology · Icahn School of Medicine at Mount Sinai
Answered on · Updated on
A lot of factors need to be considered prior to offering brain reRT in such a setting, most importantly- interval since the 1st course of RT, patient's ECOG and neurologic function, age, perceived life expectancy, size of the lesion, location of the lesion, WHO grade of glioma, patient's expectation...
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Radiation Oncology · Stony Brook University School of Medicine
Answered on
I assume that grade II glioma was treated with 54 Gy, and there was sufficient time interval for re-irradiation, and other treatment options were also discussed. I use fractionated radiourgery: 8 Gy x 4 fractions to the contrast enhancing lesion (total 32 Gy) and 6 Gy x4 to the area of new flair abn...
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