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What is your approach to managing sicca symptoms in patients not responding or not tolerating conservative measures, pilocarpine, and cevimeline?
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Mednet Member
Rheumatology · Uniformed Services University of the Health Sciences (USUHS)
- Try lower doses of pilocarpine with just 1/4 tablet at a time. Very slowly go up on the dose as tolerated. The patient's job is to find the maximum tolerated dose. I recommend this pill splitter:
- Mix capsule of cevimeline in water, just drink a tiny bit at a time tid and go up on dose as tolerated...