What is your approach to young healthy women with locally advanced breast cancer and biopsy-proven low cervical lymph nodes?

At this point, we treat them with definitive intent as most often these low cervical nodes are level 4 or adjoining level 5 node which by definition are supraclavicular nodes (often radiologists call them as cervical nodes but one needs to see images to confirm location). A subset of patients with t...

If truly localized, I take a definitive approach as well. I have trouble going from definitive intent tri-modality therapy to chemo only just because the lymph node was a cm higher than some arbitrary line we made up. No difference based on receptor status. In general, neoadjuvant chemo, then if PR/...