Mednet Logo
HomeGynecologic OncologyQuestion

What is your preferred first line systemic treatment for recurrent, metastatic, low grade, ER/PR+ pMMR endometrioid endometrial carcinoma?

4
3 Answers
Mednet Member
Mednet Member
Gynecologic Oncology · Vanderbilt University School of Medicine

Given the data presented at the most recent SGO Annual Meeting on Women's Cancer, published simultaneously in the New England Journal of Medicine, and recently endorsed by the National Comprehensive Cancer Network (NCCN), the standard of care for recurrent endometrial cancer, regardless of MMR statu...

Register or Sign In to see full answer

Mednet Member
Mednet Member
Medical Oncology · NYU Langone Medical Center

I have had a few patients with metastases (ER +) after long disease free intervals (> 10 years) who have responded very well and durably to hormonal therapy with few side effects (which include cost, etc). So I think there may still be a role for hormonal therapy in the appropriate setting (Long DFI...

Register or Sign In to see full answer

Mednet Member
Mednet Member
Gynecologic Oncology · ProMedica Toledo Hospital

Can always use cytotoxic therapy if hormonal fails.

Register or Sign In to see full answer

What is your preferred first line systemic treatment for recurrent, metastatic, low grade, ER/PR+ pMMR endometrioid endometrial carcinoma? | Mednet