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What is your preferred maintenance therapy in young, fit patients with de novo plasma cell leukemia who achieve complete response after autologous stem cell transplantation?

2 Answers
Mednet Member
Mednet Member
Medical Oncology · University of Nebraska Medical Center

Plasma cell leukemia is routinely excluded from post-transplant maintenance studies, so we cannot look to any of the randomized maintenance studies performed over the past decade. I would consider plasma cell leukemia to fit into the category of ultra-high risk myeloma, and would use lenalidomide pl...

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Mednet Member
Mednet Member
Medical Oncology · Siri Onclogy and hematology Infusion Service

If obtainable i would add daratumumab to VRD or VR ..No data but active. If stem cells left i would if fit enough do a second transplant

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