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What is your preferred treatment for refractory warm autoimmune hemolytic anemia with autoimmune neutropenia?

2 Answers
Mednet Member
Mednet Member
Hematology · University of Rochester School of Medicine and Dentistry

For immunomodulation, have you trialed IVIG? If not, this would be worth a trial.

For immunosuppression, I prefer to utilize a more T cell-directed agent after failure of steroids/rituximab. Thus, a trial of MMF or cyclophosphamide may be reasonable. I think MMF may take too long to work in a situat...

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Mednet Member
Mednet Member
Hematology · University of Rochester Cancer Center

Based on no personal experience, the literature suggests that daratumumab might be a reasonable second or third-line agent for autoimmune cytopenias.

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What is your preferred treatment for refractory warm autoimmune hemolytic anemia with autoimmune neutropenia? | Mednet