What psychiatric medications do you consider for treatment of chronic fatigue syndrome?

When a patient comes to me with a diagnosis of chronic fatigue syndrome, I know we’re dealing with something incredibly complex and deeply personal. My first job isn't to start checking boxes; it’s to sit with them and really listen. I make sure they know that their experience - the way their energy...

I think chronic fatigue could be multifactorial; therefore, a thorough assessment is required of this is primary or secondary fatigue (anemia, low vitamin D, sleep apnea, hypothyroidism, or chronic inflammatory disease, to name a few). If medical causes are determined and treated, I would start with...

First, I typically approach treatment with non-medication-based treatments such as good sleep hygiene, exercise promotion, and CBT. After this, I typically recommend supplementation of Vitamin D and B12, even if the patient's levels are not technically in the low range. I have also recommended light...

While CFS is a diagnosis of exclusion and there are different criteria depending on where you are looking, I have tried Wellbutrin with modafinil, but it did not work. Once I kept the Wellbutrin on but switched modafinil to Vyvanse, it was night and day, but this is an n=1.