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What target volumes and expansions would you use for neoadjuvant chemoradiotherapy to a large thymoma with the goal of shrinking the tumor to aid resectability?

Would you include a CTV, and if so, how would you account for proximity to the heart?
1 Answer
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Radiation Oncology · Duke University Medical Center
Answered on

Achieving an R0 resection is an important prognostic factor in thymoma. If there is concern that an R0 resection may not be realized, typically due to the proximity of the disease to the great vessels, then neoadjuvant therapy is often recommended.

At our institution, we universally recommend neoadju...

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