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What treatment modalities have you had success with for treating recalcitrant warts?

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Dermatology · Tufts University School of Medicine

More than digital warts, I find plantar warts challenging to treat. This is my usual approach:

  1. Paring down warts on feet.
  2. Multiple rounds of cryotherapy every 4-6 weeks.
  3. Between cryotherapy sessions- use of topical 5-FU with 40-70% salicylic acid
  4. After 3 rounds of cryo- if still persistent- IL Cand...

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Dermatology · Columbia University Medical Center

Compounded topical Cidofovir 1% has been great for some of my most stubborn warts, you can get it compounded, for example at Low Cost pharmacy in Noblesville, IN.

Cook et al., PMID 37801536

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Dermatology · University of Pennsylvania School of Medicine

Intralesional cidofovir works wonderfully and is now my go-to after failing cryotherapy.

Anshelevich et al., PMID 32348821

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Dermatology · Johns Hopkins Timeshare Practice

Could try Duct Tape since safe and easy. Other topical irritants may work as well. Topical sensitizers may also be useful with prolonged persistent warts.

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Dermatology · Hood River Dermatology

Have not used cidofovir, highly interested in trying this as it seems to be a novel MOA.

Have used IL Candin for many years but did not ultimately feel it was worth the extra effort and patient discomfort. I rarely use it now.

Generally, I recommend HPV vaccine, and especially in recalcitrant warts,...

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