What would you recommend as the next line treatment in a post-menopausal woman with hormone receptor positive, HER2 positive breast cancer, with progression on T-DM1 in combination with aromatase inhibitor?
Answer from: Medical Oncologist at Community Practice
Depending on the extent of disease and degree of symptoms and other prior therapies (e.g. she had trastuzumab and pertuzumab) prior to T-DM1, one could either choose tucatinib/trastuzumab/capecitabine—or if less ill or less heavily involved or asymptomatic with less disease, fulvestrant and tr...
Comments
Medical Oncologist at Mayo Clinic Rochester I would also consider trastuzumab deruxtecan...
Medical Oncologist at NYU Winthrop Hospital I would use trastuzumab deruxtecan per the Destiny...
Medical Oncologist at Mercy Clinic Oncology - Fort Smith Will you also change the endocrine therapy or do s...
Medical Oncologist at St Lukes Cancer Care Assocs I agree with Dr. @Charles L. Vogel.
I would also consider trastuzumab deruxtecan...
I would use trastuzumab deruxtecan per the Destiny...
Will you also change the endocrine therapy or do s...
I agree with Dr. @Charles L. Vogel.