What would your radiation field be for a 7.5 cm DLBCL involving the tibia (with pretibial soft tissue involvement) after CR to R-CHOP x6?

Topics: Hematologic Malignancies • Radiation Oncology • Hematology

Complete response was achieved after cycle 3. What extent of bone would you include?

Answer from: Radiation Oncologist at Academic Institution

Modern radiation fields in this setting would follow principles of involved-site radiotherapy (Yahalom et al., PMID 25863750). In the context of combined-modality therapy, radiation therapy is directed at original sites of involvement only. In this case, I would utilize pre-chemotherapy imaging (PET...

Comments

Radiation Oncologist at Alliance Cancer Care
Agree

Radiation Oncologist at Radiation Oncology of Atlanta
Similarly, a patient presents with a 12 cm longitu...

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