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When do you consider it too late after surgery to offer adjuvant chemotherapy for colon adenocarcinoma?

If a patient with stage II or III colon adenocarcinoma who presents to your clinic 12-16 weeks after surgical resection do you give adjuvant chemotherapy? Is there a time delay at which there is no benefit to adjuvant chemotherapy?
1 Answer
Mednet Member
Mednet Member
Medical Oncology · University of Texas MD Anderson Cancer Center
Answered on

Retrospective studies suggest that there are diminishing returns for adjuvant chemotherapy beginning 2-3 months after surgical resection. This is almost certainly a continuous variable, so I don't interpret this data to mean that one should never consider adjuvant chemotherapy after that time point....

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