When do you recommend prophylactic orthopaedic stablization of a long bone metastasis perceived to have high risk of pathologic fracture?

The risk of pathologic fracture is dependent on how much weight bearing the site of metastasis bears (lower extremities higher risk than upper extremities), size of the metastasis (>= 2.5 cm in the cortex of the femur is high risk), whether the lesion is lytic versus blastic (lytic is worse), and pe...