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Topics:
Adverse Events • Medical Oncology
When, if ever, do you incorporate a dental evaluation before initiating Dato-DXd to offer guidance on oral care and help limit oral toxicity?
How should this differ from evaluations done for bisphosphonates/denosumab, for example?
Answer from: Medical Oncologist at Community Practice
A formal dental evaluation can be considered, but it is unclear whether it is necessary before starting Dato-DXd. Proactive dental evaluation, when feasible, should be used, but evaluation should not delay the start of treatment. The use of good daily oral hygiene, including salt/bicarbonate and Bio...
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Answer from: Medical Oncologist at Academic Institution
In terms of risk factors for stomatitis with anticancer therapy, both intrinsic and extrinsic factors have been reported. Intrinsic factors include: age, sex, ethnicity, genetic conditions or gene polymorphisms, autoimmune diseases; and extrinsic factors include: poor oral health, diet, alcohol use,...