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When managing acute vascular compromise secondary to hyaluronic acid filler, what initial hyaluronidase dosing protocol do you employ, and do you find clinical value in traditional adjuncts like aspirin, nitroglycerin paste, or hyperbaric oxygen?

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In your acute management protocol for hyaluronic acid filler-induced vascular compromise, do you routinely use aspirin, topical nitroglycerin paste, or oral vasodilators alongside hyaluronidase? Please select all that apply.

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1 Answer
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Dermatology · UCLA
Answered on

Whether it is acute vascular compromise due to cannulating the vessel, it is now believed best to flood the area with hyaluronidase. I have 6 vials of Hylenex and 2 vials of Vitrase in my fridge at all times in case of emergency. Usually, if you are performing hyaluronic fillers, going slow and obse...

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