Topics:
Lung Cancer • Radiation Oncology • Thoracic Malignancies • Stereotactic Body Radiotherapy • Pulmonology
When should SBRT be preferred in operative patients who cannot undergo a lobectomy?
In other words, if offered wedge or segmentectomy, should SBRT be preferred? Does size matter ie if the lesion is < 3 vs < 2 vs < 1 cm? Does the chance of lymph node sampling or dissection play a lot into the decision in these sub-lobectomy resections?
Answer from: Radiation Oncologist at Academic Institution
Numerous retrospective studies have examined clinical outcomes between SBRT and surgery using a variety of different statistical tests- propensity analyses, matched-pair comparisons, multivariable analyses, and so forth. Collectively, these studies report conflicting results. No randomized...
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Answer from: Radiation Oncologist at Academic Institution
Two large randomized trials (JCOG0802/WJOG4607L; CALGB 140503) have recently been published demonstrating that small (≤ 2 cm), peripheral, node-negative NSCLCs can be effectively managed with a sublobar resection. The JCOG trial demonstrated that segmentectomy was associated with improved surviva...
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Radiation Oncologist at Jacob E Locke MD PA
Sublobar segmentectomy versus BED over 100 in PET ...
Sublobar segmentectomy versus BED over 100 in PET ...