When should SBRT be preferred in operative patients who cannot undergo a lobectomy?
In other words, if offered wedge or segmentectomy, should SBRT be preferred? Does size matter ie if the lesion is < 3 vs < 2 vs < 1 cm? Does the chance of lymph node sampling or dissection play a lot into the decision in these sub-lobectomy resections?
2 Answers
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Radiation Oncology · Duke University Medical Center
Answered on · Updated on
Numerous retrospective studies have examined clinical outcomes between SBRT and surgery using a variety of different statistical tests- propensity analyses, matched-pair comparisons, multivariable analyses, and so forth. Collectively, these studies report conflicting results. No randomized data with...
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Mednet MemberInvited Expert
Radiation Oncology · Duke University Medical Center
Answered on
Two large randomized trials (JCOG0802/WJOG4607L; CALGB 140503) have recently been published demonstrating that small (≤ 2 cm), peripheral, node-negative NSCLCs can be effectively managed with a sublobar resection. The JCOG trial demonstrated that segmentectomy was associated with improved survival c...
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