When treating a high grade neuroendocrine tumor of the rectum with involved pelvic lymph nodes, do you use the same approach (dose, fractionation, concurrent chemotherapies) as you would for a small cell lung cancer?

Topics: Radiation Oncology • Gastrointestinal Cancers

Would you use platinum/etoposide concurrent with radiation or would you opt for platinum only during radiation?

Would you use BID fractionation and to what dose?

Answer from: Radiation Oncologist at Academic Institution

I have simply used standard radiation dose and technique with platinum/etopiside or CPT/cis. Twice a day fractionation could be very difficult to tolerate. The proctitis and small bowel toxicity would probably be too severe.

Comments

Medical Oncologist at UH Seidman Cancer Center, Case Western Reserve University
I usually start with careful path review to make...

Related Questions