When would you phlebotomize patients with secondary hemochromatosis, such as due to NAFLD/cirrhosis?
HFE gene mutations in C282Y and H63D are negative.
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When do you phlebotomize patients with secondary hemochromatosis to manage iron overload?
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1 Answer
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Hematology · Weill Cornell Medical College and Houston Methodist Hospital
Answered on
My simple answer is “rarely, if ever” (but it can get much more complicated). Related to hepcidin changes, patients with chronic liver disease frequently have elevated serum ferritin and transferrin saturation, more so with alcoholic liver disease and non-alcoholic fatty liver disease. It is far fro...
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