With the RAPIDO trial demonstrating efficacy of short course XRT as part of TNT for locally advanced rectal cancer, is there a role for short course XRT to be integrated into watch and wait programs?

Topics: Radiation Oncology • Gastrointestinal Cancers

Answer from: Radiation Oncologist at Academic Institution

Great question, and one our group has discussed extensively. Our group currently uses short course radiation nearly exclusively in the treatment of locally advanced rectal cancer. One notable exception (at least so far) is if the patient desires NOM. Our rationale is that there aren’t as ...

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Radiation Oncologist at Finger Lakes Radiation Oncology Center
Please provide a “translation” of the ...

Radiation Oncologist at University of Texas MD Anderson Cancer Center
Sure. SCRT = short course radiation (5gy x ...

Radiation Oncologist at Finger Lakes Radiation Oncology Center
Thank you.

Answer from: Radiation Oncologist at Academic Institution

Great question and thank you for the shout-out, Dr. @Emma Holliday!We completed the NORMAL-R (Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum - NCT02641691) trial. This small study of 19 patients evaluated the clinical complete response (cCR) rate at 1-year (primary endpoint...

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Radiation Oncologist at University of Pennsylvania Health System
Dr. @Hyun Kim - If I may update your history a bit...

Radiation Oncologist at Washington University/Barnes-Jewish Hospital
Thank you, Dr. @Jeffrey D. Bradley! There certainl...

Radiation Oncologist at Rush University Medical Center
Thanks to all for this excellent discussion. These...

Radiation Oncologist at Anderson Regional Cancer Center
There has been debate on a different theMednet thr...

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