Would you consider giving vaginal estrogen to a patient with a history of low grade, early-stage endometrial cancer who has had a vaginal cuff recurrence (treated with radiation)?
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Do you prescribe vaginal estrogen to patients with a history of low-grade endometrial cancer with high-intermediate or high-risk features?
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2 Answers
Mednet MemberInvited Expert
Gynecologic Oncology · Washington University School of Medicine
Answered on
Yes, I would consider this... after a discussion with the patient regarding the pros and cons.
Ultimately, it would be her decision.
The risks would also be dependent on the time of recurrence and the institution of the vaginal estrogen.
Systemic absorption should be small. The biggest risk would be...
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Mednet MemberInvited Expert
Gynecologic Oncology · BayCare Medical Group
Answered on
No. Recurrence is proof of a more aggressive disease, even if salvageable. I would stick with non hormonal management of vaginal dryness.
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