Would mild hemophilia A that does not require frequent factor replacement be an absolute contraindication to anti-VEGF medications when indicated?
How would you treat metastatic, unresectable, solitary fibrous tumor in a patient with mild hemophilia A? Each anti-VEGF medication comes with a warning of hemorrhage.
Answer from: Medical Oncologist at Academic Institution
There is one report in the literature of the use of bevacizumab and chemotherapy in a patient with mild Hemophilia B and metastatic colon cancer. The patient tolerated the combination without bleeding and his hematologic monitoring remained unchanged on the combination. The package inser...
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