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Topics:
Neuro-Oncology
•
Thoracic Malignancies
•
Medical Oncology
Would you consider bevacizumab for a patient with SCLC who has asymptomatic brain metastasis progression after CNS radiation and while on maintenance immunotherapy?
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In light of Aizer et al. data presented at ASCO 2025, what is your threshold for offering SRS/SRT in patients with multiple brain metastases?
Would you add immunotherapy to chemotherapy for a patient with metastatic NSCLC, an atypical EGFR mutation, and PD-L1 ≥50% who has progressed on osimertinib?
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What are your top takeaways in Neuro Oncology from ASCO 2025?
Would you consider adding gabapentin off label for use in the treatment of glioblastoma at this time?
How would you treat a patient with newly diagnosed ALK+ Stage IIIB non-small cell lung cancer (NSCLC)?
For a patient with NSCLC harboring an EGFR or ALK mutation that transforms into SCLC, would you add immunotherapy to chemotherapy or avoid immunotherapy given the tumor's EGFR/ALK origin?
What is the expected timeframe for the development of radiation myelitis and therapies that have helped with neurologic symptoms?