Would you consider de-escalating treatment to endocrine therapy alone in a patient with prolonged NED on CDK 4/6 inhibitor + endocrine therapy?

Be good to know more specifics about her breast cancer history, whether this is administered as a first line in an endocrine sensitive setting versus not. If her history is in line with endocrine sensitivity, I think it would be reasonable to de-escalate her treatment to endocrine therapy alone and ...