Would you give a HER2 targeted agent to a patient whose initial cancer was ER/PR positive, HER2 negative but now with metastatic disease that is ER positive, PR negative, HER2 2+, FISH equivocal?   

Patient has progressed through prior lines of endocrine therapy. 

Answer from: Medical Oncologist at Academic Institution
Medical Oncologist at Memorial Sloan Kettering Cancer Center
Agree. Based on the discordant tissue biopsies and...
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