Topics:
Breast Cancer • Medical Oncology
Would you offer adjuvant chemotherapy for a patient with ER/PR (+), HER2(-) breast cancer less than 5mm in size with a high Oncotype score?
Would the exact Oncotype score guide your decision (ie closer 25-30 v. >30-35)? NCCN recommends Oncotype only for tumor size < 5mm but this case was sent by another physician.
Answer from: Medical Oncologist at Academic Institution
I don't get genomic tests in T1aN0 tumors, in fact many times the tissue is insufficient. These patients were not reflected in the studies validating these assays, and existing data suggest they have excellent prognosis.
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