Would you offer cytoreductive nephrectomy to a young, healthy patient with widely metastatic renal medullary carcinoma with partial response to cisplatin based chemotherapy?
Is there a benefit to cytoreductive nephrectomy if residual metastases are not resected? Any benefit to extending surgery to other metastatic sites?
Answer from: at Academic Institution
In the setting of widespread metastatic disease with an aggressive tumor such as medullary renal cell carcinoma, partial surgical consolidation after cisplatin-based chemotherapy is unlikely to offer a substantial durable survival benefit, unfortunately. In a patient with partial response to a point...
Very unlikely that surgery in this scenario will l...