Would you offer hypofractionated radiation regimens for a young patient with glioblastoma with good performance status but travel concerns making 6 weeks of radiation difficult?

Hypofractionated regimens are best studied in the elderly. As a neuro-oncologist I would not favor this for a young patient with good KPS, acknowledging the logistics/ hardships which unfortunately affect so many of our patients. Also, some recurrent GBM clinical trials will exclude patients who did...