Would you offer neoadjuvant chemotherapy for a large, but recurrent grade 1-2 myxoid chondrosarcoma of knee which is no longer amenable to limb salvage?
Performance status is excellent. Second surgical opinion has also confirmed need for amputation, as the recurrence is now breaching intra and extra articulate compartments. If chemo considered, what is your preferred regimen?
1 Answer
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Radiation Oncology · The Ohio State University - James Cancer Hospital and Solove Research Institute
Answered on · Updated on
While not directly relevant for this patient, it is also important to keep in mind that RT is quite effective in decreasing LF in chondrosarcoma, particularly in anatomically challenging locations like joints/pelvis/spine where wide margins often cannot be achieved.
The benefit of RT (HR 0.23 for LF...
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