Would you recommend PMRT to a clinically node positive (biopsy proven axillary node and indeterminate single IMN node) BRCA positive patient with multiple medical co-morbidities including scleroderma and ILD who is treated with neoadjuvant chemotherapy (NAC) and mastectomy who converts to ypT0/ypN0?
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1 Answers
Mednet Member
Radiation Oncology · Allegheny Health Network, Pittsburgh
Given pathological complete response and comorbidities, I would favor the omission of RT. While not a clear B-51 case, if you think IM was involved, given the totality of the situation omission is how I would go as long as post-chemo MRI showed stable or smaller IM node.