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Would you still consider adding clindamycin for streptococcal toxic shock syndrome in situations where the isolate is considered to be resistant?

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Mednet Member
Mednet Member
Infectious Disease · Early Intervention Program Camden County

I would not use clindamycin as clindamycin works by decreasing protein production specifically by binding to 50 S ribosomal subunit and disrupting the translation process. If I'm dealing with a toxin mediated pathology such as toxic shock, I prefer using linezolid.

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Would you still consider adding clindamycin for streptococcal toxic shock syndrome in situations where the isolate is considered to be resistant? | Mednet