Would you treat a uterine carcinosarcoma with omental spread with adjuvant whole abdominal radiation?

I would not offer any external beam irradiation for this patient. Even isolated omental spread in uterine carcinosarcoma represents metastatic disease. Thus, they only reasonable option is chemotherapy, usually systemic agents such as carboplatin and paclitaxel or cisplatin and ifosfamide.

I completely agree with Dr Wolfson. He was the PI for a GOG study looking at whole abdominal Radiation compared to chemotherapy for this condition .