Would you treat a young patient with de novo triple negative breast cancer metastasis to the superior mediastinum as locally advanced with chemotherapy followed by radiation or palliative chemo immunotherapy if PD-L1 positive?

Topics: Medical Oncology

Answer from: Medical Oncologist at Academic Institution

While this patient clearly meets criteria for M1 disease, if the superior mediastinum is her only site of disease beyond the breast and regional nodes I would give her 'the benefit of the doubt' and at least start her treatment with curative intent, since we can eradicate bu...

Comments

Medical Oncologist at Providence Western Washington Onc, Inc
Agree with the comments but I have been burned in...

Medical Oncologist at Springfield Clinic
Thank you, but If good response with neoadjuvant t...

Medical Oncologist at Providence Western Washington Onc, Inc
I would tend to observe after best response to in...

Medical Oncologist at Warren Alpert Medical School of Brown University
If she is free of evidence of disease after a good...

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