Would you treat rectal squamous cell carcinoma the same as rectal adenocarcinoma, stage for stage?
No, I will treat rectal squamous cell carcinoma the same as anal squamous cell carcinoma, with definitive chemoradiation with 5FU/mitomycin. If the cancer invades the posterior vaginal wall or prostate, I will also include external ilac nodes. If the tumor involves lower rectum/anus, I will also tre...
Location is everything. If the tumor approaches the anal canal, I would treat like answered above, with combined chemo/RT appropriate for squamous cell cancer of the anus. However, if the tumor starts a significant distance from the dentate line, I would consider preoperative radiation and chemother...
I have received a number of referrals from gastroenterologists for patients with “rectal SCC”. DRE usually reveals a typical mass originating in the anal canal and bridging the dentate line. I believe the “mislabeling” may occur during colonoscopy, when these are viewed by a retroflexed colonoscope....