Would you use SBRT in patients with medically inoperable renal cell carcinoma?

Topics: Radiation Oncology • Genitourinary Cancers

What is your preferred dose and fractionation? Do you utilize 4D simulation? Additionally, how conservative are your constraints for ipsilateral uninvolved kidney and contralateral kidney?

Answer from: Radiation Oncologist at Academic Institution

Yes. Together with Drs. @Rodney J. Ellis and Lee Ponsky from University Hospitals Seidman Cancer Center (UHSCC), we have published the first North American trial of SBRT for medically inoperable renal cell carcinoma. The attempt to escalate the dose from 24 Gy in 4 fxs to 48 Gy in 4 fxs was successf...

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Radiation Oncologist at Radiation Medical Group
Yes. 60 Gy/5 fx. Fiducial-guided CyberKnife SBRT. ...

Radiation Oncologist at University of Washington School of Medicine
https://www.futuremedicine.com/doi/full/10.2217/fo...

Radiation Oncologist at Mon Health
Should I ask IR to put in fiducial markers?

Radiation Oncologist at Varian Medical Systems/Allegheny health network
No need for fiducial if using SBRT platform with C...

Answer from: Radiation Oncologist at Community Practice

Agree with all the above. Even thinking of moving towards small renal masses suitable for ablation or high risk partial nephrectomy. We just completed a pilot RCT in Canada of SBRT (25 Gy/1) vs RFA (NCT03811665). Very well tolerated! No need for fiducials if using Linac based SBRT with daily CBCT. A...

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Radiation Oncologist at Jacob E Locke MD PA
What regimen for small nodular recurrence post nep...

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