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Endocrinology

General Primary Care   

Questions discussed in this category

In middle-aged adults with TSH 5–10 mIU/L and no symptoms, would you start levothyroxine or monitor, and does your threshold change with cardiovascular risk factors?
1 Answer available
How would you manage a patient who presents with hair loss that began after they started a GLP-1 inhibitor?
1 Answer available
How do you counsel patients with metabolic syndrome who decline statin therapy and have low coronary calcium scores regarding their long-term CVD risk?
3 Answers available
What is your approach to the use of GLP-1 agonists in older adults with diabetes with or at risk of sarcopenia?
3 Answers available
How many days prior to surgery do you recommend stopping SGLT2 inhibitors and when is it safe to resume therapy?
2 Answers available
When discontinuing Denosumab after more than 2-3 years of therapy, when do you recommend giving the first dose of zoledronic acid?
3 Answers available
What are some practical tips in distinguishing between metabolic bone disease due to chronic kidney disease and osteoporosis?
1 Answer available
Have any studies shown that testosterone replacement therapy lowers the incidence of prostate cancer in hypogonadal men, or is the evidence still largely neutral?
1 Answer available
How has the use of CGMs informed or improved your management of patients with pre diabetes or diabetes not on insulin?
2 Answers available
How many days prior to elective major surgery do you recommend holding oral GLP 1 R agonist therapy?
4 Answers available
Would you consider the use of romosozumab in men who have failed therapy with teriparatide and sustained multiple vertebral fractures?
Romosozumab is not currently FDA approved for men.
1 Answer available
Do you routinely prescribe vitamin D to reduce the risk of fall-related fractures in elderly patients regardless of their serum levels?
1 Answer available
When stopping denosumab and transitioning to PO bisphosphonate, do you wait for 6 months after the last denosumab injection to start PO bisphosphonate?
2 Answers available
What is the next best osteoporosis treatment option for patients who completed 2 years of teriparatide, but has contraindication to bisphosphosnate therapy (e.g. history of atypical femur fracture)?
1 Answer available
Would you use a parathyroid hormone analog for treatment of osteoporosis in a patient with mildly elevated AlkPhos of unclear etiology?
1 Answer available
Do 5HT4 agonists such as Metoclopramide actually lead to improvement in symptoms for patients with diabetes related gastroparesis?
1 Answer available
Would you start romosozumab in an active smoker?
1 Answer available
During treatment of severe osteoporosis with PTH analogs (abaloparatide), would a rise in alkaline phosphatase level >200 (in the setting of normal GGT) warrant discontinuation of medication?
There is concern for elevation in alkaline phosphatase as a precursor for bone pathology, such as an increase in risk of bone malignancy, potentially ...
1 Answer available
In patients with confirmed hypercortisolism with a high/normal unsuppressed ACTH who have both a pituitary adenoma and adrenal adenoma identified on imaging, can you reliably use DHEA-S to determine the source of cortisol production?
2 Answers available
What is the preferred first-line non-insulin agent in patients with ketosis-prone diabetes during "remission" and evidence of preserved beta cell function?
2 Answers available
What factors would lead you to extend the duration of antithyroid drug therapy in a patient with Graves' disease who is clinically euthyroid at 12 months but has risk factors for recurrence?
3 Answers available
Do you recommend routinely monitoring pancreatic markers such as amylase and lipase while receiving GLP1 R agonist or dual agonist therapies to determine their risk of pancreatitis?
2 Answers available
How do you approach the use of metformin in the management of prediabetes for patients who are neither obese nor have a family history of diabetes?
2 Answers available


Papers discussed in this category

European journal of endocrinology, 2008 Jan
TSH-receptor autoimmunity in Graves' disease after therapy with anti-thyroid drugs, surgery, or radioiodine: a 5-year prospective randomized study.
Diabetes care, 2016-11
Randomized Controlled Study of Metformin and Sitagliptin on Long-term Normoglycemia Remission in African American Patients With Hyperglycemic Crises.
Endocrinology and metabolism clinics of North America, 2022 Nov 04
Remission in Ketosis-Prone Diabetes.
Journal of clinical lipidology, 2022 Sep 11
Assessment and management of statin-associated muscle symptoms (SAMS): A clinical perspective from the National Lipid Association.
JAMA, 2021 Apr 13
Screening for Vitamin D Deficiency in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Journal of the American Geriatrics Society, 2025 Jan 29
Updating STEADI for Primary Care: Recommendations From the American Geriatrics Society Workgroup.
Diabetes research and clinical practice, 2021 Mar 08
GLP-1 receptor agonists and SGLT2 inhibitors for older people with type 2 diabetes: A systematic review and meta-analysis.
Journal of diabetes, 2025 Jun
Monitoring Sarcopenia With Incretin Receptor Activator Treatment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2025 Mar 09
Denosumab discontinuation in the clinic: implications of rebound bone turnover and emerging strategies to prevent bone loss and fractures.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2024 Oct 29
Multisociety clinical practice guidance for the safe use of glucagon-like peptide-1 receptor agonists in the perioperative period.
Nature reviews. Urology, 2022 Dec 21
The testosterone paradox of advanced prostate cancer: mechanistic insights and clinical implications.

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