Gynecologic Cancers

Vulvar Cancer   

Questions discussed in this category



Is there high quality data to support debulking in terms of oncologic outcomes? Does HPV/p53 status impact your decision?

GOG 205 treated vulvar cancer patients to a dose of 57.6 Gy to sites of gross disease, which is somewhat less than what is suggested in cases of defin...

What is considered the optimal interval from time of excision, partial, or radical vulvectomy and/or nodal dissection to initiation of post-op RT?

What factors would push towards treatment? The patient had recurrence of a pT1bN0 vulvar SCC within a year of original surgery. Re-resection shows aga...

Treat as invasive disease with concurrent chemotherapy? Any non-radiation options for large in-situ disease? If RT, would you include at least inguina...

Initial treatment of the primary invasive Paget's disease of the vulva that was metastatic to inguinal lymph node included resection and chemoradiatio...

Margins widely negative - 1cm, and full bilateral inguinofemoral lymphadenectomy performed. 

In an elderly woman who is not felt to be a good candidate for radical surgery is split course radiation alone an option for definitive intent radiati...

Vulvar cancer is well differentiated. Closest margin is 6mm. LVI is identified T1b N2c Vaginal cancer treated 20 yrs ago described as 5 cm in length...

The patient had an initial partial vulvectomy and nodal dissection 6 years prior to recurrence, with no adjuvant RT offered initially due to lack of c...

Should these patients be managed similar to p16 positive anal squamous cell carcinoma, and allowed six months or more for complete regression before c...

Surgeon is not planning vulvectomy, since biopsies showed 2 mm depth of invasion. Also tumor board felt dose to the primary site should be only about...

For definitive vulvar ca, is 5940 cGy the minimum acceptable dose for gross disease? 5760cGy? Or should the dose be escalated beyond 60Gy?


Papers discussed in this category


Gynecologic oncology, 2014-12

Gynecol. Oncol., 2015 Sep 30

Gynecol. Oncol.,

J Dermatol Case Rep,

Technology in cancer research & treatment, 2008-10

Obstetrics and gynecology, 1986-12

Gynecol Oncol, 2020 Oct 13

J Obstet Gynaecol Can,

Int J Gynecol Cancer,

Anticancer Res, 2016 Jan

Gynecol Oncol, 2021 Nov 16

Gynecol Oncol, 2019 May 18

N Engl J Med, 2023 Mar 27

N Engl J Med, 2023 Mar 27

Pract Radiat Oncol, 2019 Nov

Gynecologic oncology, 2021 Jan 23

Gynecologic oncology, 2020 Sep 24

Gynecologic oncology, 2015-06