Hematology

Hepatology

Questions discussed in this category

For pediatric patients with iron overload (high ferritin and transferrin saturation), do you perform HFE screening first, or proceed to non-HFE gene sequencing upfront to evaluate for HJV mutation as well?

Especially considering that family history is not fully available.

1 Answer available

How would you approach the management of a patient with elevated iron saturation (60%) and ferritin (500s) with negative genetic testing for hemochromatosis?

What kind of further monitoring do you perform?

1 Answer available

How would you approach a referral for concern for hemochromatosis with ferritin elevation but otherwise normal iron studies?

1 Answer available

How do you manage anticoagulation/antiplatelet therapies with strong indications for uninterrupted therapy in setting of urgent procedures?

For example, anticoagulation for recent, significant PE or dual antiplatelet therapy for recent MI, but requiring urgent procedures such as biopsy of ...

6 Answers available

In what clinical scenario would you consider liver transplant evaluation for a patient with sickle cell hepatopathy?

And should this be considered in conjunction with or sequentially with a bone marrow transplant as the actual cure for underlying hematologic disease?

1 Answer available

How do you differentiate primary from secondary iron overload?

Any unique management features for each?

1 Answer available

How do you decide whether to use pharmacologic VTE prophylaxis in hospitalized patients with decompensated cirrhosis?

How do factors like the presence of varices, severity of coagulopathy, etc., play into your decision?

2 Answers available

What is your approach to a situation where DILI is suspected secondary to an important medication (e.g., anticoagulation, antibiotics, etc.), but the diagnosis is uncertain and the liver injury is relatively mild?

Are there situations in which you would continue the possible offending agent with close monitoring?

1 Answer available

In a patient with negative Hep B surface Ag, Hep B surface antibody+, and Hep B core antibody+ serologies, do you initiate antiviral prophylaxis (e.g. entecavir) prior to starting rituximab?

5 Answers available