Pediatric Oncology

Hemostasis

Questions discussed in this category

How do you interpret a low VWF activity/antigen ratio, when both activity and antigen levels are above 50%?

E.g. Normal F8, VWF activity ~50%, VWF antigen ~100%, ratio 0.5 sent in a patient with positive bleeding history Is there any clinical significance t...

1 Answer available

Would you use PCC for clotting factor repletion in acute life threatening hemorrhage in a patient with elevated INR from coagulopathy of liver disease?

2 Answers available

When do you stop trying to eradicate an acquired factor VIII inhibitor?

Patient with high titer acquired FVIII inhibitor with no causative etiology. Bleeding is well-controlled on emicizumab, but inhibitor has failed...

3 Answers available

In patients with severe hemophilia A on emicizumab for prophylaxis, in case of noncompliance leading to a lapse of more than 2-3 months off therapy, do you reload with emicizumab?

1 Answer available

How would you manage VTE in a patient with bleeding disorder such as hemophilia?

Have you used anticoagulants other than coumadin? Or is that the only appropriate agent given monitoring is based on PT/INR?

1 Answer available

What additional testing, if any, should be performed for an adolescent patient with heavy menstrual bleeding and a negative von Willebrand disease evaluation?

1 Answer available

Are patients with bleeding disorders receiving plasma-derived products at increased risk of acquiring COVID-19?

1 Answer available

Should patients with bleeding disorders increase their home supplies of clotting factors foreseeing a possible shortage of product availability due to COVID-19?

1 Answer available

Papers discussed in this category

Haematologica, 2019 Oct 17

Bleeding disorders in adolescents with heavy menstrual bleeding in a multicenter prospective US cohort.

J Thromb Haemost,

Standardizing care to manage bleeding disorders in adolescents with heavy menses-A joint project from the ISTH pediatric/neonatal and women's health SSCs.

Blood, 2016-07-14

How I treat patients with inherited bleeding disorders who need anticoagulant therapy.

Blood, 2016 Sep 26

New concepts for anticoagulant therapy in persons with hemophilia.

Hematology. American Society of Hematology. Education Program, 2015

Coagulopathy in liver disease: a balancing act.

Pediatric Oncology

Hemostasis

Questions discussed in this category

Papers discussed in this category

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